BDBM50157060 (S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-ynyl]-phenyl}-propionic acid::CHEMBL181656

SMILES CO[C@@H](Cc1ccc(cc1)C#CCCOc1ccc(Oc2ccccc2)cc1)C(O)=O

InChI Key InChIKey=PXPYSVWYMMGIEN-VWLOTQADSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50157060   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataEC50:  1.88E+3nMAssay Description:Mean effective concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataEC50:  103nMAssay Description:Mean effective concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  3.94E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  13nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  1.15E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  1.15E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  3.94E+3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  13nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed