BDBM50157270 6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3-hydroxy-3,4,5,6-tetrahydro-2H-[1,2'']bipyridinyl-3''-carbonitrile::CHEMBL183832
SMILES Cn1cncc1C(OCc1ccc(C#N)c(n1)N1CCCC(O)C1)c1ccc(C#N)c(c1)-c1ccccc1C(F)(F)F
InChI Key InChIKey=AAWKUFHCCMHBMW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50157270
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Bovine Geranyl geranyl transeferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Bovine farnesyl transeferaseMore data for this Ligand-Target Pair