BDBM50157303 CHEMBL3785774
SMILES COc1cc2c(CC\C(=N/N3CCN(C)CC3)C2(C)C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1
InChI Key InChIKey=HRJNXIYDEXHXQM-PNFNHJRFSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50157303
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chungbuk National University
Curated by ChEMBL
Chungbuk National University
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chungbuk National University
Curated by ChEMBL
Chungbuk National University
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chungbuk National University
Curated by ChEMBL
Chungbuk National University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair