BDBM50157313 CHEMBL3786892

SMILES COc1cc2c(CCC(N)C2(C)C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=WMLFTPJTSQTLNL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157313   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50157313(CHEMBL3786892)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50157313(CHEMBL3786892)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50157313(CHEMBL3786892)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed