BDBM50157846 3-Hydroxy-7-p-tolyl-1H-furo[3,2-d]pyrimidine-2,4-dione::CHEMBL182381

SMILES Cc1ccc(cc1)-c1coc2c1[nH]c(=O)n(O)c2=O

InChI Key InChIKey=FFGCIABZEPVWCP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157846   

TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50157846(3-Hydroxy-7-p-tolyl-1H-furo[3,2-d]pyrimidine-2,4-d...)
Affinity DataIC50:  0.128nMAssay Description:Inhibitory concentration against the xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyribonuclease-1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50157846(3-Hydroxy-7-p-tolyl-1H-furo[3,2-d]pyrimidine-2,4-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DNAse1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50157846(3-Hydroxy-7-p-tolyl-1H-furo[3,2-d]pyrimidine-2,4-d...)
Affinity DataIC50:  57nMAssay Description:Inhibition of FEN1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50157846(3-Hydroxy-7-p-tolyl-1H-furo[3,2-d]pyrimidine-2,4-d...)
Affinity DataIC50:  0.0820nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed