BDBM50158025 5-Methoxy-1-(naphthalene-2-sulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL178193

SMILES COc1ccc2n(cc(C3=CCNCC3)c2c1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=XJFRLONNOVLEKR-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50158025   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158025(5-Methoxy-1-(naphthalene-2-sulfonyl)-3-(1,2,3,6-te...)
Affinity DataKi:  19nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158025(5-Methoxy-1-(naphthalene-2-sulfonyl)-3-(1,2,3,6-te...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells by microbeta liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158025(5-Methoxy-1-(naphthalene-2-sulfonyl)-3-(1,2,3,6-te...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells by microbeta liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158025(5-Methoxy-1-(naphthalene-2-sulfonyl)-3-(1,2,3,6-te...)
Affinity DataIC50:  4.10nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed