BDBM50158028 5-Fluoro-1-(naphthalene-1-sulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL182000

SMILES Fc1ccc2n(cc(C3=CCNCC3)c2c1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=MGZWJJZZEXMBMZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158028   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158028(5-Fluoro-1-(naphthalene-1-sulfonyl)-3-(1,2,3,6-tet...)
Affinity DataKi:  4nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158028(5-Fluoro-1-(naphthalene-1-sulfonyl)-3-(1,2,3,6-tet...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed