BDBM50158032 1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL362487

SMILES Clc1ccccc1S(=O)(=O)n1cc(C2=CCNCC2)c2ccccc12

InChI Key InChIKey=WJCGMHIIDQGXLP-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50158032   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158032(1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158032(1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi:  383nMAssay Description:Binding affinity against human cloned 5-hydroxytryptamine 2C receptor stably expressed in CHO cells using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158032(1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi:  599nMAssay Description:Binding affinity against human cloned 5-hydroxytryptamine 2A receptor stably expressed in CHO cells using [125I]-DOIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158032(1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi:  627nMAssay Description:Binding affinity against human cloned Dopamine receptor D3 stably expressed in CHO-K1 cells using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158032(1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity against human cloned 5-hydroxytryptamine 1A receptor stably expressed in CHO cells using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158032(1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity against human cloned Dopamine receptor D2 stably expressed in CHO-K1 cells using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158032(1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity against human cloned Dopamine receptor D4 stably expressed in CHO-K1 cells using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50158032(1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro...)
Affinity DataIC50:  8.80nMAssay Description:Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed