BDBM50159140 CHEMBL3785648

SMILES CCc1c([nH]c(C)c1C(C)=O)C(=O)NC

InChI Key InChIKey=LCSLEHAEHBSCSA-UHFFFAOYSA-N

Data  4 Kd

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159140   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to partial length human BRD4 bromodomain 1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.26E+4nMAssay Description:Binding affinity to human His-Tev tagged EP300 expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  1.81E+4nMAssay Description:Binding affinity to human His-Tev tagged CBP expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeregrin(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  3.00E+4nMAssay Description:Binding affinity to partial length human BRPF1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed