BDBM50159180 2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide::2-Chloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide

SMILES CN1CCCC1Cc1c[nH]c2ccc(NS(=O)(=O)c3ccccc3Cl)cc12

InChI Key InChIKey=JEYKBVBGFCMXAB-UHFFFAOYSA-N

Data  12 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50159180   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  15nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to human 5-hydroxytryptamine 1F receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  29.5nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  74nMAssay Description:Inhibition of [3H]-LSD binding to 5-hydroxytryptamine 7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  170nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to human 5-hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  289nMAssay Description:Inhibition of [3H]5-HT binding to human 5-hydroxytryptamine 2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  367nMAssay Description:Inhibition of [125I]DOI binding to human 5-hydroxytryptamine 2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159180(2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataEC50:  1.10nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed