BDBM50159531 CHEMBL3786148

SMILES CN1CCC(CC1)c1cc(OC2CC2)c(Nc2ncc(Cl)c(Nc3cn(C)nc3C#N)n2)cc1C

InChI Key InChIKey=SIOUACIAGFVHDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159531   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50159531(CHEMBL3786148)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human wild type ALK using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50159531(CHEMBL3786148)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human ALK L1196M mutant using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed