BDBM50160875 CHEMBL3794334::US9765054, Compound 50d

SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccc(cc1)-c1nccc(n1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=ABWQSANXEMWPFY-KZNAEPCWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160875   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM50160875(CHEMBL3794334 | US9765054, Compound 50d)
Affinity DataIC50:  210nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM50160875(CHEMBL3794334 | US9765054, Compound 50d)
Affinity DataIC50:  80nMAssay Description:Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed