BDBM50161330 (R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-3-methyl-butyramide::(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide::CHEMBL179288
SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1
InChI Key InChIKey=DGZZVIWCMGVHGV-LJQANCHMSA-N
Data 24 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50161330
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human MMP9 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human MMP2 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus pseudolysin pretreated with compound for 15 mins followed by the addition of Abz-Ala-Gly-leu-Ala-p-nitrobe...More data for this Ligand-Target Pair
Affinity DataIC50: 7.98E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin pretreated with compound for 1 hr followed by the addition of 1.73 uM bradykinin like substrate by s...More data for this Ligand-Target Pair
Affinity DataIC50: 4.16E+5nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 15 mins followed by the addition of 75 uM Abz-Ala-Gly-leu-Ala-p-n...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 1 hr followed by the addition of 3.33 uM bradykinin like substrat...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human ADAM17 after 30 mins using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human matrix metalloprotease-8More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair