BDBM50161674 3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-thiazol-2-yl-propionamide::CHEMBL359618

SMILES CS(=O)(=O)c1ccc(cc1)C(CC1CCCC1)C(=O)Nc1nccs1

InChI Key InChIKey=NEQSWPCDHDQINX-UHFFFAOYSA-N

Data  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161674   

TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161674(3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-thiaz...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration for glucokinase activation with 15 mM glucoseMore data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50161674(3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-thiaz...)
Affinity DataEC50:  2.67E+4nMAssay Description:Activation of glucokinase (unknown origin) using glucose as substrateMore data for this Ligand-Target Pair
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161674(3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-thiaz...)
Affinity DataEC50:  2.20E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair