BDBM50163650 1-(3,5-Diacetyl-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL193575

SMILES CC(=O)c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)=O

InChI Key InChIKey=XNECWHFEDUTGHE-NDIVSWGXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50163650   

TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163650(1-(3,5-Diacetyl-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-flu...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163650(1-(3,5-Diacetyl-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-flu...)
Affinity DataIC50:  2nMAssay Description:Inhibition of calcium mobilization in human eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163650(1-(3,5-Diacetyl-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-flu...)
Affinity DataIC50:  0.00700nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed