BDBM50163909 CHEMBL361922::Tyr-Pro-Phe-Phe-OCH3::Tyr-Pro-Phe-Phe-OMe

SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=YYNCXEIEPLRPCR-DZUOILHNSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50163909   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataKi:  9.07nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataKi:  9.10nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to DOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Cavia porcellus)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataIC50:  42.1nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataIC50:  42.1nMAssay Description:In vitro inhibitory concentration against Opioid receptor mu 1 was measured using guinea pig ileum assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataIC50:  37.2nMAssay Description:In vitro inhibitory concentration against Opioid receptor delta 1 was measured using mouse vas deferens assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163909(CHEMBL361922 | Tyr-Pro-Phe-Phe-OCH3 | Tyr-Pro-Phe-...)
Affinity DataIC50:  37.2nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed