BDBM50164239 6-[2-Ethyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-1-(propane-2-sulfonyl)-1H-benzoimidazol-2-ylamine; compound with methanesulfonic acid::CHEMBL191053

SMILES CCc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccc2nc(N)n(c2c1)S(=O)(=O)C(C)C

InChI Key InChIKey=OMMKUERRSBSZNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164239   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164239(6-[2-Ethyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-1...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164239(6-[2-Ethyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-1...)
Affinity DataIC50:  4.40E+3nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed