BDBM50165270 2-Fluoro-9-pent-4-ynyl-8-(3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine::CHEMBL349231

SMILES COc1cc(Cc2nc3c(N)nc(F)nc3n2CCCC#C)cc(OC)c1OC

InChI Key InChIKey=ZHJFAVDDAAUKLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165270   

TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165270(2-Fluoro-9-pent-4-ynyl-8-(3,4,5-trimethoxy-benzyl)...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed