BDBM50165303 9-Butyl-8-(2-chloro-3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine::CHEMBL191268

SMILES CCCCn1c(Sc2cc(OC)c(OC)c(OC)c2Cl)nc2c(N)ncnc12

InChI Key InChIKey=XZZRFNJYLXJJCG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165303   

TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165303(9-Butyl-8-(2-chloro-3,4,5-trimethoxy-phenylsulfany...)
Affinity DataIC50:  2.28E+4nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Mus musculus)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165303(9-Butyl-8-(2-chloro-3,4,5-trimethoxy-phenylsulfany...)
Affinity DataEC50:  850nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed