BDBM50165442 2-Amino-5-(4-bromo-phenylsulfanyl)-6-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL195782

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(Br)cc1

InChI Key InChIKey=MBMCIVJPDOZOJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165442   

TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165442(2-Amino-5-(4-bromo-phenylsulfanyl)-6-methyl-3,7-di...)
Affinity DataIC50: >2.80E+4nMAssay Description:Inhibitory concentration against human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165442(2-Amino-5-(4-bromo-phenylsulfanyl)-6-methyl-3,7-di...)
Affinity DataIC50:  460nMAssay Description:Inhibitory concentration against human thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165442(2-Amino-5-(4-bromo-phenylsulfanyl)-6-methyl-3,7-di...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory concentration against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed