BDBM50165974 CHEMBL3797688

SMILES COc1cc2c(Nc3c(F)ccc(O)c3C)ncnc2cc1OCCN1CCOCC1

InChI Key InChIKey=NRGSUVYFUYOHAT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165974   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50165974(CHEMBL3797688)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in IL3 deficient BAF3 cells assessed as reduction in cell viability after 48 hrs by CellTite...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50165974(CHEMBL3797688)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant KIF5B/RET (unknown origin) expressed in IL3 deficient BAF3 cells assessed as reduction in cell viability after 48 hrs by Ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50165974(CHEMBL3797688)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal GST fused human RET (658 to 1114 amino acid residue) using CSKtide as substrate expressed in baculovirus preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed