BDBM50166569 CHEMBL3798257

SMILES CC(NC(=O)c1ccc2[nH]nc(-c3ccnc(C)c3)c2c1)c1c(Cl)cncc1Cl

InChI Key InChIKey=IDTNHVSQAQYIPW-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50166569   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant GST-tagged ERK2 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant GST-tagged ERK1 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of IGF1R (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ALK (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT1 (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of KDR (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of RET (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ERBB2 (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of c-Src (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EPHA2 (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ABL (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166569(CHEMBL3798257)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of c-MET (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed