BDBM50166817 3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-2H-2,4,4b,9-tetraaza-fluoren-1-one::CHEMBL426650

SMILES CCOc1ccc(cc1-c1nc2c(nc3cccc(C)n23)c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1

InChI Key InChIKey=OKNUWYISANFWFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166817   

TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50:  204nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50:  9nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed