BDBM50166949 CHEMBL3798128

SMILES CSc1cnc(Nc2ccc(cc2OC(F)F)N2CCN(CC2)C(C)=O)nc1Oc1cccc(NC(=O)C=C)c1

InChI Key InChIKey=UUAOWKSAEYOOIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166949   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166949(CHEMBL3798128)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166949(CHEMBL3798128)
Affinity DataIC50:  39nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed