BDBM50167337 3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-[1,3,5]triazin-2-ylamino}-propionic acid::CHEMBL190024

SMILES NS(=O)(=O)c1ccc(CCNc2nc(Cl)nc(NCCC(O)=O)n2)cc1

InChI Key InChIKey=ZHCSUKRMPQMZHD-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50167337   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167337(3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-...)
Affinity DataKi:  1.20nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167337(3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167337(3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167337(3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-...)
Affinity DataKi:  17.9nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167337(3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-...)
Affinity DataKi:  28nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167337(3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-...)
Affinity DataKi:  29nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167337(3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-...)
Affinity DataKi:  31nMAssay Description:Inhibitory constant against human Carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167337(3-{4-Chloro-6-[2-(4-sulfamoyl-phenyl)-ethylamino]-...)
Affinity DataKi:  35nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed