BDBM50168743 (2R,3R)-1-[4-(3-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL363126
SMILES Cc1c(F)cccc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO
InChI Key InChIKey=NOBVVTLEQRHRBY-PZJWPPBQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50168743
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Rattus norvegicus)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of the compound against rat TACEMore data for this Ligand-Target Pair