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BDBM50169222 2-(aminoacetamido)acetic acid::CHEMBL292467::Gly-Gly::Gly2::N-glycylglycine::[(aminoacetyl)amino]acetic acid::glycine dipeptide::glycylglycine

SMILES: NCC(=O)NCC(O)=O

InChI Key: InChIKey=YMAWOPBAYDPSLA-UHFFFAOYSA-N

Data: 3 KI  2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50169222   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 15 member 2


(Homo sapiens)
BDBM50169222
PNG
(2-(aminoacetamido)acetic acid | CHEMBL292467 | Gly...)
Show SMILES NCC(=O)NCC(O)=O
Show InChI InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
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KEGG
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Article
PubMed
5.40E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Milano

Curated by ChEMBL


Assay Description
Binding affinity to human PepT2 in SKTP cells


Bioorg Med Chem 19: 4544-51 (2011)

More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens)
BDBM50169222
PNG
(2-(aminoacetamido)acetic acid | CHEMBL292467 | Gly...)
Show SMILES NCC(=O)NCC(O)=O
Show InChI InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
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KEGG
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Article
PubMed
1.00E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition constant (Ki) for human intestinal peptide carrier


J Med Chem 46: 5725-34 (2003)

More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens)
BDBM50169222
PNG
(2-(aminoacetamido)acetic acid | CHEMBL292467 | Gly...)
Show SMILES NCC(=O)NCC(O)=O
Show InChI InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
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PubMed
1.00E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells


J Med Chem 48: 4410-9 (2005)

More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (human))
BDBM50169222
PNG
(2-(aminoacetamido)acetic acid | CHEMBL292467 | Gly...)
Show SMILES NCC(=O)NCC(O)=O
Show InChI InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
PDB
MMDB

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n/an/a 7.24E+6n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Biological activity was measured against Angiotensin I converting enzyme


J Med Chem 38: 2705-13 (1995)

More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens)
BDBM50169222
PNG
(2-(aminoacetamido)acetic acid | CHEMBL292467 | Gly...)
Show SMILES NCC(=O)NCC(O)=O
Show InChI InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
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PubMed
n/an/an/an/a 4.80E+5n/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Activation of human PEPT1 expressed in MDCK cells


J Med Chem 49: 3636-44 (2006)

More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens)
BDBM50169222
PNG
(2-(aminoacetamido)acetic acid | CHEMBL292467 | Gly...)
Show SMILES NCC(=O)NCC(O)=O
Show InChI InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
Reactome pathway
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CHEMBL
KEGG
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PC sid
UniChem

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Article
PubMed
n/an/a 8.20E+5n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells


J Med Chem 49: 3636-44 (2006)

More data for this
Ligand-Target Pair