BDBM50171338 5-[3-(3,5-Bis-trifluoromethyl-phenyl)-ureido]-2-dimethylamino-N-(3-methoxy-propyl)-benzamide::CHEMBL363539
SMILES COCCCNC(=O)c1cc(NC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)ccc1N(C)C
InChI Key InChIKey=TTXMIASHCRWOTD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50171338
Affinity DataKi: 9.40E+3nMAssay Description:Predicted binding affinity for beta secretase by linear interaction energy continuum electrostaticsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+4nMAssay Description:Beta-secretase inhibitory activity as inhibition of secreted alkaline phosphatase in HEK293 cells expressing SEAP-APP fusion proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.84E+5nMAssay Description:Inhibitory concentration against beta-site APP cleaving enzyme (BACE-1) by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair