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BDBM50171649 CHEMBL196933::N-alkyl Gly-boro-Pro derivative

SMILES: OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCC1

InChI Key: InChIKey=DGGYQQCWHVPZRV-LBPRGKRZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171649   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast activation protein alpha


(Homo sapiens (Human))
BDBM50171649
PNG
(CHEMBL196933 | N-alkyl Gly-boro-Pro derivative)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCC1
Show InChI InChI=1S/C13H25BN2O3/c17-13(16-9-5-8-12(16)14(18)19)10-15-11-6-3-1-2-4-7-11/h11-12,15,18-19H,1-10H2/t12-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 150n/an/an/an/an/an/a



ActivX Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human FAP using Lys-Pro-AMC in fluorometric assay


Bioorg Med Chem Lett 15: 4239-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.075
BindingDB Entry DOI: 10.7270/Q2CJ8D2F
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM50171649
PNG
(CHEMBL196933 | N-alkyl Gly-boro-Pro derivative)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCC1
Show InChI InChI=1S/C13H25BN2O3/c17-13(16-9-5-8-12(16)14(18)19)10-15-11-6-3-1-2-4-7-11/h11-12,15,18-19H,1-10H2/t12-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.80n/an/an/an/an/an/a



ActivX Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human DPP4 using Gly-Pro-AMC in fluorometric assay


Bioorg Med Chem Lett 15: 4239-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.075
BindingDB Entry DOI: 10.7270/Q2CJ8D2F
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171649
PNG
(CHEMBL196933 | N-alkyl Gly-boro-Pro derivative)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCC1
Show InChI InChI=1S/C13H25BN2O3/c17-13(16-9-5-8-12(16)14(18)19)10-15-11-6-3-1-2-4-7-11/h11-12,15,18-19H,1-10H2/t12-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80n/an/an/an/an/an/a



ActivX Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay


Bioorg Med Chem Lett 15: 4239-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.075
BindingDB Entry DOI: 10.7270/Q2CJ8D2F
More data for this
Ligand-Target Pair