BDBM50172463 1-(2-Fluoro-4'-trifluoromethyl-biphenyl-4-yl)-cyclopropanecarboxylic acid::CHEMBL196246

SMILES OC(=O)C1(CC1)c1ccc(c(F)c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=STSYUQWYKFKDNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172463   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172463(1-(2-Fluoro-4'-trifluoromethyl-biphenyl-4-yl)-cycl...)
Affinity DataIC50:  2.20E+4nMAssay Description:Concentration required to inhibit A beta 40 peptide 100 umMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172463(1-(2-Fluoro-4'-trifluoromethyl-biphenyl-4-yl)-cycl...)
Affinity DataIC50:  1.11E+5nMAssay Description:Inhibitory concentration against beta-amyloid-42 (Abeta42) secretion was evaluated in human neuroglioma cells (H4-APP695NL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed