BDBM50172465 1-(4,2',2''-Trifluoro-[1,1';4',1'']terphenyl-4''-yl)-cyclopropanecarboxylic acid::CHEMBL427548

SMILES OC(=O)C1(CC1)c1ccc(c(F)c1)-c1ccc(c(F)c1)-c1ccc(F)cc1

InChI Key InChIKey=PYLGXNLJVJXKBA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172465   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172465(1-(4,2',2''-Trifluoro-[1,1';4',1'']terphenyl-4''-y...)
Affinity DataIC50:  5.79E+4nMAssay Description:Inhibitory concentration against beta-amyloid-42 (Abeta42) secretion was evaluated in human neuroglioma cells (H4-APP695NL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172465(1-(4,2',2''-Trifluoro-[1,1';4',1'']terphenyl-4''-y...)
Affinity DataIC50:  4.60E+4nMAssay Description:Interaction with human cytochrome P450 isoform 2C19 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172465(1-(4,2',2''-Trifluoro-[1,1';4',1'']terphenyl-4''-y...)
Affinity DataIC50:  7.00E+3nMAssay Description:Interaction with human cytochrome P450 isoform 2C9 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50172465(1-(4,2',2''-Trifluoro-[1,1';4',1'']terphenyl-4''-y...)
Affinity DataIC50:  3.80E+4nMAssay Description:Interaction with human cytochrome P450 isoform 3A4 expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed