BDBM50172727 CHEMBL3808853
SMILES CC1COC(=O)Nc2cccc(CNC(=O)C(Nc3ccc4c(N)nccc4c3)c3ccc1cc3)c2
InChI Key InChIKey=XQDFKGVDOCCXNS-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50172727
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 46nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of purified human factor 10a using S2765 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 1.08E+4nMAssay Description:Inhibition of purified human factor 11a after 30 to 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair