BDBM50173477 (S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentyl]-3-(3,5-dibromo-4-hydroxy-phenyl)-2-{3-[2-(3-methoxy-phenyl)-ethyl]-ureido}-propionamide::CHEMBL198925

SMILES COc1cccc(CCNC(=O)N[C@@H](Cc2cc(Br)c(O)c(Br)c2)C(=O)N[C@H](CCCCN)C(=O)N2CCN(CC2)c2ccncc2)c1

InChI Key InChIKey=QRTDBPVYMKZTKN-IHLOFXLRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173477   

TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173477((S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-...)
Affinity DataIC50:  7.05E+4nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]-CGRP as radioligand after 180 minutes of incubation at pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50173477((S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-...)
Affinity DataIC50:  200nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed