BDBM50174013 (E)-3-(3-(6-isopropylquinolin-8-yl)phenyl)-2-(4-(methylsulfonyl)phenyl)acrylic acid::CHEMBL197386

SMILES CC(C)c1cc(-c2cccc(\C=C(\C(O)=O)c3ccc(cc3)S(C)(=O)=O)c2)c2ncccc2c1

InChI Key InChIKey=SRUGDVLQDNLYGA-CVKSISIWSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174013   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174013((E)-3-(3-(6-isopropylquinolin-8-yl)phenyl)-2-(4-(m...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory activity against PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174013((E)-3-(3-(6-isopropylquinolin-8-yl)phenyl)-2-(4-(m...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory activity against PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174013((E)-3-(3-(6-isopropylquinolin-8-yl)phenyl)-2-(4-(m...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174013((E)-3-(3-(6-isopropylquinolin-8-yl)phenyl)-2-(4-(m...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed