BDBM50174024 8-(3-(1-(4-chlorophenyl)-2-(pyridin-4-yl)ethyl)phenyl)-6-isopropylquinoline::CHEMBL382545

SMILES CC(C)c1cc(-c2cccc(c2)C(Cc2ccncc2)c2ccc(Cl)cc2)c2ncccc2c1

InChI Key InChIKey=WKUVVAFTNFZIQC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174024   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174024(8-(3-(1-(4-chlorophenyl)-2-(pyridin-4-yl)ethyl)phe...)
Affinity DataIC50:  6.40nMAssay Description:Inhibitory activity against PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174024(8-(3-(1-(4-chlorophenyl)-2-(pyridin-4-yl)ethyl)phe...)
Affinity DataIC50:  11.8nMAssay Description:Inhibitory activity against PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174024(8-(3-(1-(4-chlorophenyl)-2-(pyridin-4-yl)ethyl)phe...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174024(8-(3-(1-(4-chlorophenyl)-2-(pyridin-4-yl)ethyl)phe...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity against PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed