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BDBM50174345 CHEMBL3809112

SMILES: N[C@@H](Cc1cccc(Cc2ccccc2)c1)C(O)=O

InChI Key: InChIKey=WDAJRFDYHJVFMA-HNNXBMFYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174345   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Large neutral amino acids transporter small subunit 1


(Homo sapiens (Human))
BDBM50174345
PNG
(CHEMBL3809112)
Show SMILES N[C@@H](Cc1cccc(Cc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C16H17NO2/c17-15(16(18)19)11-14-8-4-7-13(10-14)9-12-5-2-1-3-6-12/h1-8,10,15H,9,11,17H2,(H,18,19)/t15-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.30E+3n/an/an/an/an/an/a



University of Nebraska Kearney

Curated by ChEMBL


Assay Description
Inhibition of human LAT1 expressed in HEK cells assessed as reduction in uptake of [3H]-gabapentin after 3 mins by scintillation counting based cis-i...


Bioorg Med Chem Lett 26: 2616-2621 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.023
BindingDB Entry DOI: 10.7270/Q2ZS2ZFD
More data for this
Ligand-Target Pair