BDBM50175274 CHEMBL3809864::US10189809, Compound I-97
SMILES Nc1ccnc(n1)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1
InChI Key InChIKey=NSGAFVFYXLWWOI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50175274
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to KOP receptor (unknown origin) at 10 uMMore data for this Ligand-Target Pair
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals
US Patent
Ironwood Pharmaceuticals
US Patent
Affinity DataEC50: <2.00E+4nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Agonist activity at KOP receptor (unknown origin)More data for this Ligand-Target Pair