BDBM50175483 3-{2-[4-(4,5-dichloro-2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3a':4,5]thieno[2,3-d]pyrimidin-4-one::CHEMBL197338

SMILES COc1cc(Cl)c(Cl)cc1N1CCN(CCn2cnc3sc4CN(C)CCc4c3c2=O)CC1

InChI Key InChIKey=PGGSJVILXJSING-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175483   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50175483(3-{2-[4-(4,5-dichloro-2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50175483(3-{2-[4-(4,5-dichloro-2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  4.90nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed