BDBM50175690 (4-(4-(5-(3-amino-3-ethylpentyl)thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone::CHEMBL382945

SMILES CCC(N)(CC)CCc1ccc(s1)-c1ccnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)n1

InChI Key InChIKey=OHOGGIZZDHRWBN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175690   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175690((4-(4-(5-(3-amino-3-ethylpentyl)thiophen-2-yl)pyri...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against IKK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175690((4-(4-(5-(3-amino-3-ethylpentyl)thiophen-2-yl)pyri...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against IKK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50175690((4-(4-(5-(3-amino-3-ethylpentyl)thiophen-2-yl)pyri...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against IKK complex isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed