BDBM50175692 CHEMBL370166::N-(2-aminoethyl)-4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)benzamide

SMILES NCCNC(=O)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1

InChI Key InChIKey=SFJIDFPJXATQEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175692   

LigandPNGBDBM50175692(CHEMBL370166 | N-(2-aminoethyl)-4-(4-(benzo[b]thio...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against IKK complex isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175692(CHEMBL370166 | N-(2-aminoethyl)-4-(4-(benzo[b]thio...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against IKK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175692(CHEMBL370166 | N-(2-aminoethyl)-4-(4-(benzo[b]thio...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against IKK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed