BDBM50175833 3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(4-chlorophenyl)propanamide::CHEMBL371730
SMILES Clc1ccc(NC(=O)CCN2CCC(Cc3cnc[nH]3)CC2)cc1
InChI Key InChIKey=PXZWAKNYGHYHEV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50175833
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in guinea pig brainMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
The Schering Plough Research Institute
Curated by ChEMBL
The Schering Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in human brainMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
The Schering Plough Research Institute
Curated by ChEMBL
The Schering Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from histamine H1 receptor in guinea pig brainMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
The Schering Plough Research Institute
Curated by ChEMBL
The Schering Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair