BDBM50175927 1-phenyl-8-((1S,2S)-2-p-tolyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL371906

SMILES Cc1ccc(cc1)[C@@H]1CCCC[C@@H]1N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key InChIKey=DBRILGNGHLWVTH-ZEQRLZLVSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175927   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175927(1-phenyl-8-((1S,2S)-2-p-tolyl-cyclohexyl)-1,3,8-tr...)
Affinity DataEC50:  85nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium- and chloride-dependent glycine transporter 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175927(1-phenyl-8-((1S,2S)-2-p-tolyl-cyclohexyl)-1,3,8-tr...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT2 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed