BDBM50175960 8-[(cis, rac)-2-(4-chloro-phenyl)-2-hydroxy-cyclohexyl]-1-(4-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL200621

SMILES COc1ccc(cc1)N1CNC(=O)C11CCN(CC1)[C@@H]1CCCC[C@@]1(O)c1ccc(Cl)cc1

InChI Key InChIKey=GNWJPBZDDXTBAA-ZEQKJWHPSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175960   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175960(8-[(cis, rac)-2-(4-chloro-phenyl)-2-hydroxy-cycloh...)
Affinity DataEC50:  99nMAssay Description:Displacement of [3H]glycine from human GlyT1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175960(8-[(cis, rac)-2-(4-chloro-phenyl)-2-hydroxy-cycloh...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175960(8-[(cis, rac)-2-(4-chloro-phenyl)-2-hydroxy-cycloh...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175960(8-[(cis, rac)-2-(4-chloro-phenyl)-2-hydroxy-cycloh...)
Affinity DataEC50:  2.50E+4nMAssay Description:Displacement of [3H]glycine from human GlyT2 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed