BDBM50176273 (S)-1-(1H-pyrrolo[2,3-f]isoquinolin-1-yl)propan-2-amine::CHEMBL202656

SMILES C[C@H](N)Cn1ccc2ccc3cnccc3c12

InChI Key InChIKey=DBBQAOGBHMWNBA-JTQLQIEISA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50176273   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176273((S)-1-(1H-pyrrolo[2,3-f]isoquinolin-1-yl)propan-2-...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]5HT from human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176273((S)-1-(1H-pyrrolo[2,3-f]isoquinolin-1-yl)propan-2-...)
Affinity DataKi:  778nMAssay Description:Displacement of [3H]5HT from human 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176273((S)-1-(1H-pyrrolo[2,3-f]isoquinolin-1-yl)propan-2-...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [125I]DOI from human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176273((S)-1-(1H-pyrrolo[2,3-f]isoquinolin-1-yl)propan-2-...)
Affinity DataEC50:  152nMAssay Description:Binding to human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176273((S)-1-(1H-pyrrolo[2,3-f]isoquinolin-1-yl)propan-2-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Binding to human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176273((S)-1-(1H-pyrrolo[2,3-f]isoquinolin-1-yl)propan-2-...)
Affinity DataEC50:  297nMAssay Description:Binding to human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed