BDBM50177029 CHEMBL3814269

SMILES COc1ccc(Br)cc1\C=c1/sc2nc(=O)c(C)nn2c1=O

InChI Key InChIKey=UEMYVTYHECWXSR-WDZFZDKYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177029   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Riken

Curated by ChEMBL
LigandPNGBDBM50177029(CHEMBL3814269)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human Plk1 PBD (326 to 603 residues) using 5-carboxyfluorescein-GPMQSpTPLNG-OH as substrate incubated for 1 hr prior to addition of sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Riken

Curated by ChEMBL
LigandPNGBDBM50177029(CHEMBL3814269)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human Plk3 PBD (335 to 646 residues) using 5-carboxyfluorescein-GPLATSpTPKNG-OH as substrate incubated for 1 hr prior to addition of su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Riken

Curated by ChEMBL
LigandPNGBDBM50177029(CHEMBL3814269)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human Plk2 PBD (355 to 685 residues) using 5-carboxyfluorescein-GPMQTSpTPKNG-OH as substrate incubated for 1 hr prior to addition of su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed