BDBM50177059 3-Cyclooctyl-9-dimethylamino-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::9-dimethylamino-3-cyclooctyl-3H-5-thia-1,3,6-triazafluoren-4-one::CHEMBL223399

SMILES CN(C)c1ccnc2sc3c(ncn(C4CCCCCCC4)c3=O)c12

InChI Key InChIKey=FVEOBLKOMQNQJN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177059   

TargetMetabotropic glutamate receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177059(3-Cyclooctyl-9-dimethylamino-3H-pyrido[3',2':4,5]t...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Rat)
Biocampus

Curated by ChEMBL
LigandPNGBDBM50177059(3-Cyclooctyl-9-dimethylamino-3H-pyrido[3',2':4,5]t...)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177059(3-Cyclooctyl-9-dimethylamino-3H-pyrido[3',2':4,5]t...)
Affinity DataIC50:  179nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed