BDBM50177108 2-alpha,3-alpha-di(4-methylphenyl)tropane::2-beta,3-beta-di(4-methylphenyl)tropane::CHEMBL426178

SMILES CN1C2CCC1[C@@H]([C@@H](C2)c1ccc(C)cc1)c1ccc(C)cc1

InChI Key InChIKey=DTGXSBMWMFLEGI-OEXSPLCWSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50177108   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177108(2-alpha,3-alpha-di(4-methylphenyl)tropane | 2-beta...)
Affinity DataKi:  910nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177108(2-alpha,3-alpha-di(4-methylphenyl)tropane | 2-beta...)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177108(2-alpha,3-alpha-di(4-methylphenyl)tropane | 2-beta...)
Affinity DataIC50:  1.30E+4nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177108(2-alpha,3-alpha-di(4-methylphenyl)tropane | 2-beta...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177108(2-alpha,3-alpha-di(4-methylphenyl)tropane | 2-beta...)
Affinity DataIC50:  340nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed