BDBM50177251 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-pentanoyl-piperazine-2-carboxylic acid pyrazin-2-ylamide::CHEMBL201904

SMILES CCCCC(=O)N1CCN(CC1C(=O)Nc1cnccn1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12

InChI Key InChIKey=DRYADWZEQIWQDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177251   

LigandPNGBDBM50177251(4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity against Ha-Ras processing in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177251(4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against farnesyltransferase quantified by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed