BDBM50177453 4-{3-[4-(biphenyl-4-sulfonyl)-[1,4]diazepane-1-carbonyl]-benzyl}-2H-phthalazin-1-one::CHEMBL372778

SMILES O=C(N1CCCN(CC1)S(=O)(=O)c1ccc(cc1)-c1ccccc1)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key InChIKey=WEYRKSAFPKQVCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177453   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50177453(4-{3-[4-(biphenyl-4-sulfonyl)-[1,4]diazepane-1-car...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed