BDBM50178168 CHEMBL3814246::US10206931, Example 176
SMILES COc1ccc(cc1OC)-c1cccc2NC(=O)C[C@@H](C)Nc12
InChI Key InChIKey=TUDUFFGDXQMAHC-LLVKDONJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50178168
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged BRD4 bromodomain-1 (unknown origin) incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to CBP (unknown origin) expressed in HEK293 cells after overnight incubation by luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged CBP (unknown origin) incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair